TransMedics Group, Inc., Dassault Systèmes, and Hasbro Top List of New England’s Largest Leases
BOSTON – Boston Real Estate Times, New England’s leading real estate digital, print and video production media, is pleased to announce its much-anticipated annual ranking of the largest leases in New England for the year 2025-2026.
Based on area leased in square feet, our list highlights the most dynamic transactions of 2025, driving both innovation and economic growth.
1. TransMedics Group, Inc. at Assembly Innovation Park
Assembly Square, Somerville, MA
Size: 498,000 SF
Type: Full-building
Landlord: BioMed Realty
2. Dassault Systèmes at 175 and 185 Wyman Street
175 & 185 Wyman Street, Waltham, MA
Size: 320,000 SF
Type: Mixed-use
Landlord: Hobbs Brook Real Estate
3. Hasbro at 400 Summer Street
400 Summer Street, Boston, MA
Size: 265,000 SF
Type: Office
Landlord: WS Development
125 Summer St., Boston, MA
Size: 256,000 SF
Type: Office
Landlord: Oxford Properties
5. Goodwin at 200 Fifth Avenue
200 Fifth Avenue, New York City, NY
Size: 244,000 SF
Type: Office
Landlord: BXP
6. Lila Sciences at Alewife Park
1 & 5 Alewife Park, Cambridge, MA
Size: 235,500 SF
Type: Life sciences
Landlord: IQHQ Inc.,
Broker Representing Tenant: Newmark
Broker Representing Landlord: Colliers
7. GSC USA at 175 Pioneer Drive
175 Pioneer Drive, Leominster, MA
Size: 231,000 SF
Type: Manufacturing
Landlord: Arris Partners
Broker Representing Tenant: Savills
Broker Representing Landlord: Arris Partners
8. DSV at Crossroads Industrial
1045 Richmond Highway, Stafford, VA
Size: 219,456 SF
Type: Warehouse
Landlord: Matan Companies
9. WilmerHale at 60 State Street
60 State Street, Boston, MA
Size: 201,018 SF
Type: Office
Landlord: Starwood REIT
Broker Representing Tenant: Savills
Broker Representing Landlord: JLL
10. State Street Corporation at The District Burlington
District Ave, Burlington, MA
Size: 162,000 SF
Type: Office
Landlord: National Development
11. Commonwealth Financial Network at 275 Wyman Street
275 Wyman Street, Waltham, MA
Size: 151,765 SF
Type: Office
Landlord: Hobbs Brook Real Estate
Broker Representing Tenant: Newmark
Broker Representing Landlord: CBRE
12. Rockland Trust at One Tech Campus
1 Technology Place, Rockland, MA
Size: 140,000 SF
Type: Office
Landlord: A.W. Perry
13. KKR at Two International Place
2 International Place, Boston, MA
Size: 132,529 SF
Type: Office
Landlord: The Chiofaro Company, PGIM Real Estate
Brokers Representing Landlord: JLL; Newmark; Cushman & Wakefield
14. Cooley LLP at 725 12th Street
725 12th Street, Washington, D.C.
Size: 126,000 SF
Type: Office
Landlord: BXP
15. DraftKings at 225 Franklin St.
225 Franklin St., Boston, MA
Size: 125,000 SF
Type: Office
Landlord: Oxford Properties
16. New England Appliance Group at 206 Mechanic Street
206 Mechanic Street, Bellingham, MA
Size: 124,000 SF
Type: Full-building
Landlord: Marcus Partners
17. Organogenesis Holdings Inc. at 100 Technology Way
100 Technology Way, Smithfield, RI
Size: 123,000 SF
Type: Full-building
Landlord: The Davis Companies
Broker Representing Tenant: JLL
Broker Representing Landlord: Newmark
18. Foot Locker at 570 Carillon
570 Carillon Parkway, St. Petersburg, FL
Size: 111,000 SF
Type: Office
Landlord: The Feil Organization
Broker Representing Tenant: JLL
Broker Representing Landlord: CBRE
19. REXA at The Campus at Canopy Drive
Canopy Drive, Middleborough, MA
Size: 110,000 SF
Type: Manufacturing
Landlord: VMD Companies
Broker Representing Landlord: CBRE
1 Milestone Street, Boston, MA
Size: 100,000 SF
Type: Mixed-use
Landlord: Tishman Speyer; Breakthrough Properties; The Harvard Allston Land Company
21. Red Thread at 4 Executive Place
4 Executive Place, Andover, MA
Size: 96,000 SF
Type: Industrial
Landlord: Marcus Partners
22. Intelligent Manufacturing Solutions at 12 Innovation Way
12 Innovation Way, Londonderry, NH
Size: 86,954 SF
Type: Industrial
Landlord: R.J. Kelly
Broker Representing Landlord: Newmark
23. Dentsply Sirona Inc. at 590 Lincoln Street
590 Lincoln Street, Waltham, MA
Size: 84,413 SF
Type: Office, Manufacturing
Landlord: Hobbs Brook Real Estate
Broker Representing Tenant: Cushman & Wakefield
Broker Representing Landlord: CBRE
24. Eli Lilly and Co. at 645 Summer Street
645 Summer Street, Boston, MA
Size: 75,000 SF
Type: Full-building
Landlord: Oxford Properties
25. Generate:Biomedicines at Innovation Park
4 Corporate Drive, Andover, MA
Size: 75,000 SF
Type: Laboratory
Landlord: IQHQ Inc.
